On 10th May 1946, Krishna Jivrajani said to Bhagavan:
During Sadhana I feel that something is going up. Is that right or should it go down?
Bhagavan: Never mind, whether something goes up or down.Does it exist without you? Never forget that. Whatever experience may come, remember who has the experience and thus cling to "I" or the Self.
Jivarajani: Suppose there is some disturbance during meditation,such as mosquito bites, should one persist in meditation and try to bar the bites and ignore the interruption or drive the mosquitoes away and then continue the meditation?
Bhagavan:You must do as you find most convenient. You will not attain mukti simply because you refrain from driving the mosquitoes away. Nor being denied mukti simply because you drive them away. The thing is to attain is one pointedness and then attain mano nasa. Whether you do this by putting up with the mosquito bites or driving the mosquitoes away is left to you.If you are completely absorbed in your meditation, you will not know that the mosquitoes are biting you.Till you attain that stage why should you not drive away them away?
(Recall Bhagavan Ramana staying inside the Patalalingam shrine for many days and when He was lifted and brought out, the devotees found His thighs oozing blood with insect and scorpion bites and there was puss formation too!)
Source: Arunachala's Ramana, Boundless Ocean of Grace,Volume 5. Sri Ramanasramam, Tiruvannamalai)